Dioctahedral smectite

Oral
Chronic diarrhoea

Powder for oral susp: Stir thoroughly in half glass of water. For children, add 50 mL of water and stir thoroughly in the feeding bottle, or mix with a semi-liquid food (e.g. broth, stewed fruit, mashed vegetables, baby food).

Intestinal occlusion. Children. Pregnancy and lactation.

Gastrointestinal disorders: Rarely, aggravation of constipation.

May interfere with the absorption of other substances when administered simultaneously.

Description: Dioctahedral smectite has a powerful coating property on the gastrointestinal mucosa. It protects the gastrointestinal mucosa by interacting with glycoprotein of mucus thus increasing the resistance of the mucosal gel as a response to aggressive agents.
Synonym: diosmectite.
Pharmacokinetics:
Absorption: Not absorbed.
Metabolism: Not metabolised.
Excretion: Via faeces.

Store below 25°C.

Antidiarrheals

A07BC05 - diosmectite ; Belongs to the class of other intestinal adsorbents.

Buckingham R (ed). Smectites. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 03/04/2020.

Dehecta (Daewoong Pharmaceutical Co., Ltd). MIMS Philippines. http://www.mims.com/philippines. Accessed 03/04/2020.

Dehecta (Daewoong Pharmaceutical Co., Ltd). MIMS Thailand. http://www.mims.com/thailand. Accessed 07/04/2020.

Smecta (Beaufour Ipsen Industrie). MIMS Singapore. http://www.mims.com/singapore. Accessed 03/04/2020.

Smecta Orange-Vanilla (Beaufour Ipsen Industrie). MIMS Thailand. http://www.mims.com/thailand. Accessed 03/04/2020.

Smecta® (Dioctahedral Smectite): Not Recommended for Use in Children Aged Below 2 Years and Pregnant or Breastfeeding Women. National Pharmaceutical Regulatory Agency - Ministry of Health Malaysia. https://www.npra.gov.my/. Accessed 07/04/2020.