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The total daily dose may vary from 1-4 tabs taken orally. The dose should be adjusted according to the individual patient's response, commencing with 40-80 mg daily and increasing until adequate control is achieved. A single dose should not exceed 160 mg and when higher doses are required, a twice-daily split dosage is advised and should be divided according to the main meals of the day.
In the majority of cases, 2 tabs/day with meals, 1 tab with breakfast, 1 tab with dinner.
For the elderly diabetic, the starting dose should be ½ tab in the evening.
