THIAMINE HYDROCHLORIDE BP: Very large doses of thiamine administered parenterally may produce neuromuscular and ganglionic blockade and neurologic symptoms. Treatment is supportive.
CYANOCOBALAMIN BP: Even in large doses, vitamin B12 isn't usually toxic.
LYSINE HYDROCHLORIDE USP: Overdose of L-lysine could increase cholesterol levels and cause gallstones. High L-lysine intake can also cause diarrhea and stomach cramps.
PYRIDOXINE HYDROCHLORIDE BP: Usually nontoxic; adverse neurologic effects, nausea, headache, paresthesia, somnolence, increased serum AST, decreased serum folic acid concentrations, Ataxia, sensory neuropathy.