Curam Side Effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.
Conditions the patient needs to look out for: Allergic reactions: skin rash; inflammation of blood vessels (vasculitis) which may be visible as red or purple raised spots on the skin, but can affect other parts of the body; fever, joint pain, swollen glands in the neck, armpit or groin; swelling, sometimes of the face or throat (angioedema), causing difficulty in breathing; collapse.
Contact a doctor immediately if the patient gets any of these symptoms. Stop taking Curam.
Inflammation of large intestine: Inflammation of the large intestine, causing watery diarrhoea usually with blood and mucus, stomach pain and/or fever.
Contact the doctor as soon as possible for advice if the patient gets these symptoms.
Very common side effects (may affect more than 1 in 10 people): diarrhoea (in adults).
Common side effects (may affect up to 1 in 10 people): thrush (candida - a yeast infection of the vagina, mouth or skin folds); feeling sick (nausea), especially when taking high doses. If affected take Curam with a meal; vomiting; diarrhoea (in children).
Uncommon side effects (may affect up to 1 in 100 people): skin rash, itching; raised itchy rash (hives); indigestion; dizziness; headache.
Uncommon side effects that may show up in the blood tests: increase in some substances (enzymes) produced by the liver.
Rare side effects (may affect up to 1 in 1,000 people): skin rash, which may blister, and looks like small targets (central dark spots surrounded by a paler area, with a dark ring around the edge - erythema multiforme).
If the patient notices any of these symptoms contact a doctor urgently.
Rare side effects that may show up in the blood tests: low number of cells involved in blood clotting; low number of white blood cells.
Frequency not known (frequency cannot be estimated from the available data): Other side effects have occurred in a very small number of people but their exact frequency is unknown.
Allergic reactions (see previously mentioned).
Inflammation of the large intestine (see previously mentioned).
Inflammation of the protective membrane surrounding the brain (aseptic meningitis).
Serious skin reactions: a widespread rash with blisters and peeling skin, particularly around the mouth, nose eyes and genitals (Stevens-Johnson syndrome), and a more severe form, causing extensive peeling of the skin (more than 30% of the body surface - toxic epidermal necrolysis); widespread red skin rash with small pus-containing blisters (bullous exfoliative dermatitis); a red, scaly rash with bumps under the skin and blisters (exanthemous pustulosis); flu-like symptoms with a rash, fever, swollen glands, and abnormal blood test results (including increased white blood cells (eosinophilia) and liver enzymes) (Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)).
Contact a doctor immediately if the patient gets any of these symptoms: inflammation of the liver (hepatitis); jaundice, caused by increases in the blood of bilirubin (a substance produced in the liver) which may make your skin and whites of the eyes appear yellow; inflammation of tubes in the kidney; blood takes longer to clot; hyperactivity; convulsions (in people taking high doses of Curam or who have kidney problems); black tongue which looks hairy; stained teeth in children, usually removed by brushing (oral suspension only).
Side effects that may show up in the blood or urine tests: severe reduction in the number of white blood cells; low number of red blood cells (haemolytic anaemia); crystals in urine.
Reporting of side effects: If the patient gets any side effects, talk to the doctor or pharmacist. This includes any possible side effects not listed in this monograph.
The patient can also report side effects directly via the national reporting system. By reporting side effects the patient can help provide more information on the safety of this medicine.