IV Administer as continuous IV infusion w/in 60 min for adult or 30 min for childn & adolescent.
Advanced head & neck cancer 200 mg once wkly for 6 wk in combination w/ radiotherapy &/or chemotherapy. Maintenance: 200 mg every 15 days until the patient's general condition permits.
Nasopharyngeal carcinoma 200 mg once wkly for 8 wk in combination w/ radiation. Maintenance: 200 mg every 15 days until the patient's general condition permits.
Inoperable esophageal malignancy w/ epithelial origin 200 mg once wkly during 6 wk concomitantly w/ standard radiotherapy &/or chemotherapy.
Glioma Adult 200 mg wkly in combination w/ conventional radiation treatment. Maintenance: 200 mg every 15 days until the patient's general condition permits.
Childn & adolescent Monotherapy in 2 consecutive phases: Induction phase: 150 mg/m
2 wkly for 6 wk. Consolidation phase: 150 mg/m
2 every 3 wk until disease progression, to be given in patient w/o progressive disease upon 8th wk of evaluation after induction.
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