Patient Medicine Information
Why do I need this medicine?
Chlortalidone is used to treat water retention caused by heart failure, liver or kidney disease. Water retention may be noticed as swelling of the feet, ankles, lower leg and hands or shortness of breath. For this reason, it is commonly known as a "water pill".

Chlortalidone is also used to treat high blood pressure.

Chlortalidone may also be used to treat other medical conditions, as decided by your doctor.
How do I take this medicine?
Take Chlortalidone exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Take Chlortalidone with food. Try to take it at the same time each day.

You will feel the urge to pass urine more often while being treated with Chlortalidone. Take it early in the day to avoid waking up frequently at night to go to the toilet.

Chlortalidone must be taken regularly for it to work well. Continue taking Chlortalidone even when you feel better. Do not stop taking it unless instructed by your doctor.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Alert your doctor if you:

- are unable to pass urine
- have Addison's disease (a disorder of the adrenal glands)
- are allergic to sulfonamides (e.g. sulfa-containing antibiotic)
as Chlortalidone may not be suitable for you.
What should I take note of while taking this medicine?
Inform your doctor if you have the following conditions:

- diabetes
- gout
- high cholesterol
- liver disease
- kidney disease
- systemic lupus erythematosus (SLE) – autoimmune disease that causes inflammation

Let your doctor know if you are pregnant or breastfeeding.

If you are going for an operation, including minor surgery and dental work, inform your doctor or dentist that you are taking Chlortalidone.

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medicine regularly. He may also need to do routine blood tests while you are being treated with Chlortalidone.

What lifestyle changes can I make to improve my blood pressure?

Regular exercise and eating a healthy diet will help lower your blood pressure and improve your overall health. Engage in physical activity (e.g. walking) at least 30 to 60 minutes on most days of the week. If you have not exercised for a long time, start with light exercises such as slow walks. Speak to your doctor about what type of exercise would be suitable for you. Follow a healthy diet plan by eating more fruits, vegetables, whole grains and low-fat dairy products and reduce your intake of foods high in saturated fat, cholesterol and sodium. Cutting down on deep-fried foods and using less salt when cooking can kick-start your healthy diet.

If you smoke, you should try to quit. Smoking is harmful to your blood pressure, heart and overall health. Speak to your doctor or pharmacist about ways to kick your smoking habit.
What side effects could I experience?
Chlortalidone may cause weakness and dizziness. If affected, do not drive or take part in any activity in which you need to be alert. You may feel dizzy when getting up from a sitting or lying down position, especially if you are taking Chlortalidone for the first time. This is normal and should go away as you get used to the medicine. It will help if you get up slowly.

You may need to pass urine more often while you are being treated with Chlortalidone. As your body adjusts to the medicine, this urination effect should also decrease.

Chlortalidone may also cause any of the following side effects: loss of appetite, nausea, vomiting, diarrhoea, stomach cramps, thirst and sensitivity to sunlight. Apply sunscreen when going outdoors and avoid direct or prolonged exposure to sunlight and UV lamps.

Other side effects may be serious, although they are not common. Alert your doctor quickly if you experience:

- severe thirst
- muscle cramps
- fast or irregular heart beat
- frequent and persistent sore throat with fever or unusual bleeding or bruising
- rashes with skin peeling or blisters

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Inform your doctor and pharmacist if you are taking any of these medicines:

- medicines for heart disease or high blood pressure e.g. digoxin, enalapril
- NSAIDs (medicines for pain and inflammation) e.g. indometacin
- medicines for diabetes e.g. glipizide
- corticosteroids (medicines for inflammation) e.g. prednisolone
- ciclosporin (medicine used in organ transplants or certain immune disorders)
- lithium (medicine for mood)
- allopurinol (medicine for gout)

This list does not include all medicines that may interact with Chlortalidone.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicine, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Your doctor may give you potassium supplements while you are being treated with Chlortalidone. Alternatively, he may tell you to eat more of foods that are high in potassium, such as orange juice, bananas or prunes.

Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on chlortalidone-oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2022 MIMS. All rights reserved. Powered by
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