Carvedilol is usually well tolerated. Symptomatic postural hypotension, mainly on the initiation of therapy or when increasing the dose may occur, but the incidence is minimized when Carvipress is used as recommended. Dizziness, headache, fatigue, gastrointestinal upset and bradycardia have been observed. These are usually mild, transient and occur early in the course of treatment.
Diminished peripheral circulation, dry eyes and flu-like symptoms have occurred. Occasionally, stuffy nose, wheezing, depressed mood, sleep disturbance, paraesthesiae and progression of heart failure have been reported in isolated cases. There have been isolated reports of changes in serum transaminases, thrombocytopenia and leukopenia.