Dosage must be individualized. Blood pressure response is dose related over the range of 2-32 mg.
Usual Recommended Starting Dose: 16 mg once daily when used as monotherapy in patients who are not volume depleted. Candesartan cilexetil can be administered once or twice daily with total daily doses ranging from 8-32 mg. Larger doses do not appear to have a greater effect. Most of the antihypertensive effect is present within 2 weeks and maximal blood pressure reduction is generally obtained within 4-6 weeks of candesartan cilexetil treatment.