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Vitamin D Toxicity: Adverse effects of Calomin Inj (calcitriol inj) are, in general, similar to those encountered with excessive vitamin D intake. The early and late signs and symptoms of vitamin D intoxication associated with hypercalcemia include: Early: Weakness, headache, somnolence, nausea, vomiting, dry mouth, constipation, muscle pain, bone pain and metallic taste.
Late: Polyuria, polydipsia, anorexia, weight loss, nocturia, conjunctivitis (calcific), pancreatitis, photophobia, rhinorrhea, pruritus, hyperthermia, decreased libido, elevated blood urea nitrogen (BUN), albuminuria, hypercholesterolemia, elevated aspartate aminotransferase (AST) and alanine transaminase (ALT), ectopic clarification, hypertension, cardiac arrhythmias and rarely, overt psychosis.
Occasional mild pain on injection have been observed.
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