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Acute pain
Adult: Lumbar block in labour pain: 0.25% soln: 15-30 mg (6-12 mL); 0.375% soln: 22.5-45 mg (6-12 mL); 0.5% soln: 30-60 mg (6-12 mL). Alternatively, 0.1% soln: 10-15 mg (10-15 mL) per hr; 0.125% soln: 10-15 mg (8-12 mL) per hr via infusion. Caudal block in labour pain: 0.25% soln: 25-50 mg (10-20 mL); 0.375% soln: 37.5-75 mg (10-20 mL); 0.5% soln: 50-100 mg (10-20 mL).
Child: 1-12 yr Caudal/Lumbar/Thoracic epidural block: 0.25% soln: 1.5-2 mg/kg. Field block/Peripheral nerve block: 0.25 or 0.5% soln: 0.5-2 mg/kg.
Child: 1-12 yr Caudal/Lumbar/Thoracic epidural block: 0.25% soln: 1.5-2 mg/kg. Field block/Peripheral nerve block: 0.25 or 0.5% soln: 0.5-2 mg/kg.
Parenteral
Postoperative pain
Adult: 0.1% soln: 4-15 mg (4-15 mL) per hr; 0.125% soln: 5-15 mg (4-12 mL) per hr via epidural infusion. 1.3% liposomal susp: Bunionectomy: 106 mg (8 mL) as single dose (7 mL into surrounding tissues and 1 mL into SC tissue); haemorrhoidectomy: 266 mg (20 mL) as single dose, diluted to 30 mL preservative-free 0.9% NaCl for inj and infiltrated around the anal sphincter in 6 equally-divided portions.
Parenteral
Surgical anaesthesia
Adult: Local infiltration: 0.25% soln: Up to 150 mg (60 mL). Peripheral nerve block: 0.25% soln: 12.5 mg (5 mL); 0.5% soln: 25 mg (5 mL); doses of up to 150 mg may also be given. Retrobulbar block in ophth surgery: 0.75% soln: 15-30 mg (2-4 mL). Sympathetic nerve block: 0.25% soln: 50-125 mg (20-50 mL). Lumbar epidural block: 0.25% soln: 25-50 mg (10-20 mL); 0.5% soln: 50-100 mg (10-20 mL); 0.75% soln in non-obstetric surgery: 75-150 mg (10-20 mL) as single dose. Caudal block: 0.25% soln: 37.5-75 mg (15-30 mL); 0.75% soln: 75-150 mg (15-30 mL). Spinal block: 0.5% soln: 10-20 mg (2-4 mL).
