Buphenine: Indication, Dosage, Side Effect, Precaution

This information is not country-specific. Please refer to the Myanmar prescribing information.

Generic Medicine Info

Indications and Dosage

Oral
Cerebrovascular and peripheral vascular disease

Adult: 3-12 mg 3-4 times/day, up to 90 mg/day.

Contraindications

MI, hyperthyroidism, paroxysmal tachycardia, severe angina.

Special Precautions

Peptic ulcers, tachyarrhythmias, uncompensated CCF. Pregnancy and lactation.

Adverse Reactions

Trembling, nervousness, weakness, dizziness, palpitations, nausea, vomiting, anaemia.

Action

Description: Buphenine is a sympathomimetic that produces peripheral vasodilatation via stimulation of beta-adrenoceptors. It also acts directly on the arteries and arterioles of the skeletal muscles. It also suppresses uterine contractility thereby preventing premature labour.

MIMS Class

Peripheral Vasodilators & Cerebral Activators

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