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Safety in pregnancy has not been established. Rare reports of congenital anomalies have been reported following intrauterine exposure of HMG-CoA reductase inhibitors. HMG-CoA reductase inhibitors are not recommended for use during pregnancy. An interval of 1 month should be allowed from stopping Avas treatment to conception in the event of planning a pregnancy.
Use of HMG-CoA reductase inhibitors during breastfeeding is not recommended, because of the potential for serious adverse effects in nursing infants.
