As an adjunct to diet to reduce elevated total-C, LDL-C, apo B and TG levels in patients with primary hypercholesterolemia (heterozygous familial and nonfamilial) and mixed dyslipidemia (Frederickson Types IIa and IIb).
Adjunctive therapy to diet for the treatment of patients with elevated serum triglycerides (Frederickson Type IV).
Treatment of patients with primary dysbetalipoproteinemia (Frederickson Type III) who does not respond adequately to diet.
Reduction of total and LDL-C in patients with homozygous familial hypercholesterolemia as an adjunct to other lipid-lowering treatments (eg, LDL apheresis) or if such treatments are unavailable.