Avas Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Warnings Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions MIMS Class ATC Classification Regulatory Classification Presentation/Packing Brand Resources

Concise Prescribing Info

Contents

Atorvastatin

Indications/Uses

As an adjunct to diet to reduce elevated total-C, LDL-C, apo B & triglyceride levels in patients w/ primary hypercholesterolemia (heterozygous familial & nonfamilial) & mixed dyslipidemia (Frederickson types IIa & IIb). Adjunctive therapy to diet for the treatment of patients w/ elevated serum triglycerides (Frederickson type IV). Treatment of patients w/ primary dysbetalipoproteinemia (Frederickson type III) who do not respond adequately to diet. Reduction of total & LDL-C in patients with homozygous familial hypercholesterolemia as an adjunct to other lipid-lowering treatments.

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Dosage/Direction for Use

Hypercholesterolemia (heterozygous familial & nonfamilial) & mixed dyslipidemia (Frederickson type IIa & IIb) Starting dose: 10 mg daily. Dosage range: 10-80 mg once daily. Homozygous familial hypercholesterolemia 10-80 mg daily.

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Overdosage

View Avas overdosage for action to be taken in the event of an overdose.

Administration

May be taken with or without food: Avoid excessive consumption (>1 L/day) of grapefruit juice.

Contraindications

Hypersensitivity. Active liver disease or unexplained persistent elevations of serum transaminase (>3x the ULN). Pregnancy & lactation.

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Warnings

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Special Precautions

Perform liver function tests prior to start of treatment & periodically thereafter. Excessive alcohol intake. History of liver disease. Discontinue therapy in acute serious condition suggestive of a myopathy or having a risk factor predisposing to the development of renal failure secondary to rhabdomyolysis. Childn. Elderly.

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Use In Pregnancy & Lactation

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Adverse Reactions

Constipation, flatulence, dyspepsia, abdominal pain, headache, nausea, myalgia, diarrhoea, asthenia, insomnia.

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Drug Interactions

Erythromycin, OC, digoxin, cyclosporine, fibric acid derivatives, azole antifungals or niacin, Mg & Al-containing antacids. Decreased prothrombin time w/ warfarin.

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Action

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MIMS Class

Dyslipidaemic Agents

ATC Classification

C10AA05 - atorvastatin ; Belongs to the class of HMG CoA reductase inhibitors. Used in the treatment of hyperlipidemia.

Regulatory Classification

POM

Presentation/Packing

Form

Avas FC tab 10 mg

Packing/Price

3 × 10's

Form

Avas FC tab 20 mg

Packing/Price

3 × 10's

Avas

atorvastatin

Manufacturer:

Micro Labs

Distributor:

Zizawa Healthcare