Dose range: 5-40 mg once daily. Hyperlipidemia, mixed dyslipidemia, hypertriglyceridemia, primary dysbetalipoproteinemia (type III hyperlipoproteinemia) & slowing of the progression of atherosclerosis
10 mg once daily. Heterozygous familial hypercholesterolemia in ped patients (10-17 yr)
5-20 mg/day. Max: 20 mg/day. Adjustment dose at intervals of ≥4 wk. Homozygous familial hypercholesterolemia
20 mg. Use w/ cyclosporine or lopinavir/ritonavir
5 mg. Max: 10 mg. Concomitant lipid-lowering therapy
10 mg daily. Severe renal impairment
5 mg once daily. Max: 10 mg. All doses to be taken once daily.