Use in pregnancy: Salicylates should be used during pregnancy only when the potential benefits justify the possible risks to the fetus. Aspirex generally, should be avoided during the last 3 months (although low dosages have been useful in the prevention of preeclampsia during this period) of pregnancy (especially during the 1-2 weeks before delivery). Similarly, aspirin in fixed combination with extended-release dipyridamole should be avoided in the 3rd trimester of pregnancy.
Use in lactation: Since salicylates are distributed into milk in low concentrations, Aspirex should be administered with caution to nursing women or should be avoided due to possible risk of Reye's syndrome.