Treatment: Salicylate overdose should be emptied in the stomach by lavage. Salicylate remaining in the stomach may be adsorbed by activated charcoal. Fluid and electrolyte management is the mainstay treatment with the immediate aim being correction of acidosis, hyperpyrexia, hypokalemia and dehydration. Alkaline diuresis, haemodialysis or haemoperfusion are effective methods of removing salicylate from the plasma.