Pregnancy and lactation: Although animal studies did not reveal any toxic effects on fertility or fetal development (Pregnancy category B), ARTRODAR should not be administered during pregnancy. In addition, ARTRODAR should not be prescribed to lactating women due to reports that small amounts of diacerein derivatives pass into the maternal milk.
ARTRODAR should not be prescribed to children below 18 years old as no clinical studies have been undertaken in this age group.
Effects on ability to drive and use machines: No sedative effect, which may affect the ability to handle machines, is known for diacerein.