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In adult: For both hypertension and angina the usual initial dose is 5 mg ALMOBEST once daily which may be increased to a maximum dose of 10 mg depending on the individual patient's response.
No dose adjustment of ALMOBEST is required upon concomitant administration of thiazide diuretics, beta blockers, and angiotensin-converting enzyme inhibitors.
Use in children: Not recommended.
Use in elderly: ALMOBEST, used at similar doses in elderly or younger patients, is equally well tolerated. Therefore normal dosage regimens are recommended.
Patients with hepatic impairment: See "Precautions".
Patients with renal impairment: Changes in amlodipine plasma concentrations are not correlated with degree of renal impairment, therefore the normal dosage is recommended. Amlodipine is not dialysable.
