Myelosuppression (leucopenia, neutropenia, thrombocytopenia), anaemia, epistaxis; immunosuppression w/ elevated infection rate; hyperuricaemia; ECG alterations typical for ischaemia; bronchospasm; potentially life-threatening mucositis (eg, stomatitis, pharyngitis, oesophagitis, proctitis), anorexia, watery diarrhoea, nausea & vomiting; alopecia, delayed wound healing, hand-&-foot syndrome associated w/ dysaesthesia & reddening, swelling, pain & desquamation of skin in palms & soles; exhaustion, general asthenia, fatigue, lack of impulse, fever. Febrile neutropenia, angina pectoris-like chest pain.