Increased risk of incident depression; history of or risk factors for QT prolongation, osteoporosis. Men at risk of developing ureteric obstruction or spinal cord compression. Preexisting DM; known depression, HTN; MI, cardiac failure; reduced bone mineral density. Women at risk of developing ovarian hyperstimulation syndrome, w/ PCOS; increased cervical resistance; vag bleeding. Monitor for signs or symptoms of abdominal haemorrhage. Patients w/ low BMI &/or receiving full anticoagulation medications. Chronic alcohol abusers, smokers. +ve reactions in anti-doping tests. Long-term therapy w/ anticonvulsants or corticosteroids. Concomitant use w/ medicinal products prolonging QT interval; anti-androgens. Combination w/ tamoxifen. Use non-hormonal contraceptive methods. Not to be used during pregnancy. Not recommended during lactation. Not to be used in childn.