Discontinue use in case of allergic or anaphylactic-type reactions. Decompensated cardiac insufficiency, HTN, oesophageal varices, pulmonary oedema, haemorrhagic diathesis, severe anaemia, renal & post-renal anuria. Ensure adequate hydration. Monitor against circulatory overload & hyperhydration. Monitor electrolyte status. Control coagulation & haematocrit. Hypervolaemia.