Add-on therapy w/ intranasal corticosteroids (INC) for adults ≥18 yr w/ chronic rhinosinusitis w/ nasal polyps (CRSwNP) for whom therapy w/ INC does not provide adequate disease control. Adults & adolescents ≥12 yr: Moderate to severe persistent allergic asthma whose symptoms are inadequately controlled w/ inhaled corticosteroids. Add-on therapy for chronic spontaneous urticaria (CSU) w/ inadequate response to H
1-antihistamine treatment. Childn 6 to <12 yr: Add-on therapy to improve asthma control w/ severe persistent allergic asthma who have +ve skin test or
in vitro reactivity to perennial aeroallergen & frequent daytime symptoms or night-time awakenings & who have had multiple documented severe asthma exacerbation despite daily high-dose inhaled corticosteroids + long-acting inhaled β
2-agonist.
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