Xofluza

Xofluza Description

baloxavir marboxil

Manufacturer:

Roche

Distributor:

Zuellig Pharma
Full Prescribing Info
Description
XOFLUZA (baloxavir marboxil) is an antiviral PA endonuclease inhibitor.
The active component of XOFLUZA is baloxavir marboxil.
The chemical name of baloxavir marboxil is ({(12aR)-12-[(11S)-7,8-Difluoro-6,11-dihydrodibenzo[b,e]thiepin11-yl]-6,8-dioxo-3,4,6,8,12,12a-hexahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazin-7-yl}oxy)methylmethyl carbonate. The empirical formula of baloxavir marboxil is C27H23F2N3O7S.
Baloxavir marboxil has a molecular mass of 571.55 grams per mole and a partition coefficient (log P) of 2.26. It is freely soluble in dimethylsulfoxide, soluble in acetonitrile, slightly soluble in methanol and ethanol, and practically insoluble in water.
Excipients/Inactive Ingredients: The inactive ingredients of XOFLUZA are: croscarmellose sodium, hypromellose, lactose monohydrate, microcrystalline cellulose, povidone, sodium stearyl fumarate, talc, and titanium dioxide.
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