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Xanax

Xanax

alprazolam

Manufacturer:

Viatris

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Alprazolam
Indications/Uses
Anxiety states (anxiety neuroses), mixed anxiety-depression, neurotic or reactive depression, panic-related disorders.
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Dosage/Direction for Use
Anxiety Initially 0.75-1.5 mg daily in divided doses. Usual dosage range: 0.5-4 mg daily in divided doses. Depression Initially 1.5 mg daily in divided doses. Usual dosage range: 1.5-4.5 mg daily in divided doses. Panic disorders Initially 0.5-1 mg at bedtime or 0.5 mg tds. Usual dosage range: Adjusted according to patient's response in increments not >1 mg daily every 3-4 days. Elderly Initially 0.5-0.75 mg daily in divided doses, adjusted according to patient's response.
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Overdosage
View Xanax overdosage for action to be taken in the event of an overdose.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity to benzodiazepines, alprazolam.
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Special Precautions
Anaphylaxis & angioedema. Habituation & emotional/physical dependence. History of alcoholism or drug abuse. Abuse-prone individuals. Depressed or suicidal patients. Complex sleep-related behaviors. Avoid abrupt discontinuation due to w/drawal symptoms. Not recommended in concomitant use w/ ketoconazole, itraconazole, other azole-type antifungals. Concomitant use w/ nefazodone, fluvoxamine, cimetidine; fluoxetine, propoxyphene, OCs, diltiazem, macrolides. May affect ability to drive & use machines. Renal or hepatic impairment. Pregnancy. Not to be used during lactation. Childn <18 yr.
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Adverse Reactions
Depression; sedation, somnolence, ataxia, memory impairment, dysarthria, dizziness, headache; constipation, dry mouth; fatigue, irritability. Decreased appetite; confusional state, disorientation, libido changes, anxiety, insomnia, nervousness; balance disorder, abnormal coordination, attention disturbance, hypersomnia, lethargy, tremor; blurred vision; nausea; dermatitis; sexual dysfunction; increased/decreased wt.
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Drug Interactions
Increased risk of resp depression, profound sedation, coma & death w/ benzodiazepines. Co-administration w/ ketoconazole, itraconazole or other azole-type antifungals; nefazodone, fluvoxamine, cimetidine; fluoxetine, propoxyphene, OCs, diltiazem or macrolides eg, erythromycin & troleandomycin. Impaired clearance, prolonged elimination t½ & enhanced clinical effects w/ HIV PIs eg, ritonavir. Increased digoxin conc.
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Caution For Usage
For caution against possible variation of physical aspect of medicine... Click to view Xanax detailed prescribing information
Storage
View Xanax storage conditions for details to ensure optimal shelf-life.
Description
View Xanax description for details of the chemical structure and excipients (inactive components).
Action
View Xanax mechanism of action for pharmacodynamics and pharmacokinetics details.
MIMS Class
Anxiolytics
ATC Classification
N05BA12 - alprazolam ; Belongs to the class of benzodiazepine derivatives anxiolytics. Used in the management of anxiety, agitation or tension.
Presentation/Packing
Form
Xanax tab 0.25 mg
Packing/Price
100's
Form
Xanax tab 0.5 mg
Packing/Price
100's;5 × 100's (RM430.7/box)
Form
Xanax tab 1 mg
Packing/Price
100's
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