Ufur Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Warnings Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Tegafur 100 mg, uracil 224 mg

Indications/Uses

Remission of subjective & objective symptoms in head & neck, gastric, colorectal, liver, gallbladder, bile duct, pancreatic, lung, breast, bladder, prostatic & uterine cervical cancers. CRC in combination w/ folinate.

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Dosage/Direction for Use

300-600 mg daily in 2-3 divided doses. Uterine cervical cancer Total dose: 600 mg daily in 2-3 doses. Doses may apply to combination regimen w/ other antineoplastics. Combination therapy w/ folinate for CRC Adult Tegafur 300-600 mg + folinate 75 mg daily in 3 divided doses. Repeat a course of 28-day consecutive administration, followed by 7-day rest period.

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Overdosage

View Ufur overdosage for action to be taken in the event of an overdose.

Administration

Should be taken on an empty stomach: Take at least 1 hr before or after meals.

Contraindications

Hypersensitivity. Concomitant therapy w/ sorivudine. Pregnancy & lactation.

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Warnings

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Special Precautions

Bone marrow depression. Monitor hematologic, hepatic & renal function. Infectious diseases, varicella, gastric or duodenal symptoms, glucose intolerance, heart disease. Patients on or previously treated w/ chemotherapy. Hepatic & renal impairment. Childn. Elderly.

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Use In Pregnancy & Lactation

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Adverse Reactions

Bone marrow depression, fulminant hepatitis, dehydration, severe enteritis, leukoencephalopathy, anosmia, interstitial pneumonia, silence angina.

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Drug Interactions

Serious blood dyscrasia & GI disorder w/ tegafur, gimeracil & oteracil K. Enhanced warfarin K. Elevated blood conc w/ sorivudine. Intensified phenytoin action. Exaggerated ARs w/ other antimalignant tumor agents or radiation therapy.

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Storage

View Ufur storage conditions for details to ensure optimal shelf-life.

Description

View Ufur description for details of the chemical structure and excipients (inactive components).

Action

View Ufur mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Cytotoxic Chemotherapy

ATC Classification

L01BC53 - tegafur, combinations ; Belongs to the class of antimetabolites, pyrimidine analogues. Used in the treatment of cancer.

Regulatory Classification

Presentation/Packing

Form

Ufur cap

Packing/Price

70's

Ufur

tegafur + uracil

Manufacturer:

TTY Biopharm

Distributor:

Pharm-D