Tofisopam: Indication, Dosage, Side Effect, Precaution

This information is not country-specific. Please refer to the Malaysia prescribing information.

Generic Medicine Info

Indications and Dosage

Oral
Alcohol withdrawal syndrome, Short-term management of anxiety

Adult: 50-100 mg 1-3 times daily.

Contraindications

Aggressive-impulsive psychopathy. Pregnancy.

Special Precautions

Discontinue if sleep disturbances occur. Avoid sleep disturbances by taking last dose earlier (e.g. before 5 pm).

Adverse Reactions

Nausea, rash, epigastric pain, itching, extreme liveliness, hyperactivity, aggressiveness.

Action

Description:
Mechanism of Action: Tofisopam is a 2,3-benzodiazepine related structurally to the 1,4-benzodiazepines e.g. diazepam. It is however, lacking in the sedative, anticonvulsant and muscle relaxant properties of the conventional benzodiazepines.

MIMS Class

Anxiolytics

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