Tiratricol: Indication, Dosage, Side Effect, Precaution

This information is not country-specific. Please refer to the Malaysia prescribing information.

Generic Medicine Info

Contraindications

Untreated thyrotoxicosis of any aetiology; uncorrected adrenal insufficiency; arteriosclerosis; pregnancy.

Special Precautions

Only for specific approved indications and under strict medical supervision, not as a treatment for obesity. CV disorders; elderly; DM; diabetes insipidus; adrenal cortical insufficiency.

Adverse Reactions

Fatigue; lethargy; profound wt loss; severe diarrhoea. Abnormal thyroid function test.
Potentially Fatal: Heart attacks and stroke.

Overdosage

Hypermetabolic state similar to thyrotoxicosis.

Drug Interactions

Increased hypoprothrombinaemic effect of anticoagulants; increased risk of coronary insufficiency with sympathomimetic agents; additive effects with thyroid drugs.

Lab Interference

Alter thyroid function tests.

Action

Description:
Mechanism of Action: Tiratricol is a metabolite of tri-iodothyronine and has thyroid hormone activity. It is given by mouth to suppress TSH secretion. It is found in dietary supplements for weight loss.

MIMS Class

Thyroid Hormones

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