Siu Guan


Averroes Pharma
Concise Prescribing Info
Edema of various etiology including cardiac & renal edema. Mild to moderate HTN.
Dosage/Direction for Use
Initially 20-50 mg IM/IV. Larger doses: 20-mg increments not >2-hrly. Max: 1,500 mg daily. Childn 0.5-1.5 mg/kg daily. Max: 20 mg daily.
Hypersensitivity to furosemide, sulphonamides. Hypovolemia or dehydration, anuria, renal failure, hepatic coma, severe hypokalemia, severe hyponatremia, precomatose & comatose states associated w/ hepatic encephalopathy. Lactation.
Special Precautions
Prostatic hypertrophy, impaired micturition. Correct hypotension or hypovolemia before starting therapy. Monitor serum Na, K & creatinine regularly. Latent diabetes, gout, hepatorenal syndrome, hypoproteinemia. High risk for radiocontrast nephropathy. May affect ability to drive or operate machinery. Pregnancy. Premature infants.
Adverse Reactions
Thrombocytopenia, reduced serum Ca levels, nephrocalcinosis/nephrolithiasis in premature infants, serum cholesterol & triglyceride levels may rise, decreased glucose tolerance, reduced BP, itching, urticaria, rashes or bullous lesions, erythema multiforme, exfoliative dermatitis, purpura, electrolyte & water imbalance. Hypovolemia & dehydration in elderly. Acute urine retention. Local reactions in IM administration. Increased blood creatinine & urea levels. Increased uric acid serum levels.
Drug Interactions
More pronounced fall in BP w/ cardiac glycosides, diuretics, antihypertensive agents. Marked fall in BP w/ ACE inhibitors or angiotensin II receptor antagonists. Reduced effect by sucralfate, probenecid, MTX. Increased serum lithium levels, salicylate toxicity. Attenuated antidiabetic, pressor agents effects & potentiated salicylates, theophylline, curare-type muscle relaxant effects. Potentiated ototoxicity of aminoglycosides. Enhanced nephrotoxicity of cisplatin. Attenuated effect by phenytoin. Increased risk of hyponatremia w/ carbamazepine or aminoglutethimide. Corticosteroids may cause Na retention. Increased risk of hypokalemia w/ carbenoxolone, liquorice, β2-sympathomimetics, laxatives, reboxetine, amphotericin. Renal function impairment w/ high doses cephalosporins. Increased risk of gouty arthritis w/ ciclosporin.
MIMS Class
ATC Classification
C03CA01 - furosemide ; Belongs to the class of high-ceiling sulfonamide diuretics.
Suopinchon soln for inj 20 mg/2 mL
100 × 1's
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