Discontinue use if severe dehydration or electrolyte imbalance occurs. Signs of atropinism particularly in Down syndrome patients. Risk of drug dependence. Ensure appropriate fluid & electrolyte therapy. Prolonged use or high doses. Concomitant use w/ alcohol, barbiturates, tranquilizers. May affect ability to drive & operate machinery. Patients w/ advanced hepatorenal disease & abnormal hepatic function. Pregnancy & lactation. Not recommended in childn <6 yr. Elderly.
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