Sulfanilamide: Indication, Dosage, Side Effect, Precaution

This information is not country-specific. Please refer to the Malaysia prescribing information.

Generic Medicine Info

Indications and Dosage

Vaginal
Vulvovaginal candidiasis

Adult: As vaginal cream: 1 applicatorful (about 6 g of 15% cream) once or bid for 30 days. As vaginal suppository: 1 suppository (1.05 g) bid for 7 days.

Contraindications

Sensitivity to sulfonamides; lactation.

Special Precautions

Pregnancy (3rd trimester), G6PD deficiency. Discontinue if rash occurs.

Adverse Reactions

Increased discomfort or burning sensation.

Pregnancy Category (US FDA)

Topical/Vag: C

Action

Description:
Mechanism of Action: Sulfanilamide is a short-acting sulfonamide with antibacterial activity is less than that of sulfamethoxazole. It interferes with the synthesis of nucleic acids in sensitive organisms by blocking the conversion of p-aminobenzoic acid (PABA) to the co-enzyme dihydrofolic acid.

MIMS Class

Sulphonamides

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