Not to be used IA, intrabursally or for intratendinous & epidural administration for local effect. Avoid deltoid muscle inj, intrathecal route. Discontinue use in Kaposi's sarcoma patients. Not for treatment of traumatic brain injury. Not to be used in cerebral malaria & active ocular herpes simplex. Not recommended in optic neuritis. Left ventricular free wall rupture after recent MI; hypothalamic-pituitary adrenal axis suppression, Cushing's syndrome, hyperglycemia; susceptibility to infections; exacerbated systemic fungal & intercurrent infections; latent or active amebiasis; known or suspected Strongyloides (threadworm) infestation; active or latent TB; posterior subcapsular cataracts, glaucoma; CHF, HTN; active or latent peptic ulcers, diverticulitis, fresh intestinal anastomoses, non-specific ulcerative colitis; osteoporosis; neuromuscular transmission disorders eg, myasthenia gravis; psychic derangements, aggravated existing emotional instability or psychotic tendencies; pheochromocytoma. Monitor IOP in therapy >6 wk. Dietary salt restriction & K supplementation. Avoid abrupt w/drawal. Avoid exposure to chicken pox or measles. Not to be used w/ live or live, attenuated vaccine. Concomitant use w/ neuromuscular-blocking drugs eg, pancuronium. May affect ability to drive & use machines. Renal insufficiency; cirrhosis. Pregnancy & lactation. Elderly ≥65 yr.