Individualized dosing.
Soliqua 10-40 pen Insulin-naive patient Initially 10 u/5 mcg (10 dose steps). Dose may be titrated up to 40 dose steps.
Patient on ≥20 to <30 u insulin glargine Initially 20 u/10 mcg (20 dose steps). Dose may be titrated up to 40 dose steps.
Soliqua 30-60 pen Patient on ≥30 to ≤60 u insulin glargine Initially 30 u/10 mcg (30 dose steps). Max daily dose: Insulin glargine 60 u & lixisenatide 20 mcg (60 dose steps). Continue titration w/ Soliqua 30-60 pen up to 60 dose steps for doses >40 dose steps daily.