Sojourn

Sojourn

sevoflurane

Manufacturer:

Piramal Critical Care

Distributor:

Unimed
Concise Prescribing Info
Contents
Sevoflurane
Indications/Uses
Induction & maintenance of general anaesth in adults & childn for in- & outpatient surgery.
Dosage/Direction for Use
Induction Individualized dosage. Anaesth induction in unpremedicated patient Inspired conc of up to 8%. Maintenance: 0.5-3%.
Contraindications
Hypersensitivity to sevoflurane or other halogenated agents. Known or suspected genetic susceptibility to malignant hyperthermia.
Special Precautions
Increased risk in patients w/ known sensitivity to volatile halogenated anaesth agents. Dose-dependent BP decrease; malignant hyperthermia; seizures. Peri-op hyperkalaemia in patients w/ latent & overt neuromuscular disease particularly Duchenne muscular dystrophy. Desiccated CO2 absorbent replacement. Transient elevation in glucose & WBC count. Monitor urine flow during therapy. May affect ability to drive & operate machinery. Concomitant use w/ succinylcholine. Severe hepatic dysfunction; underlying hepatic conditions or use w/ drugs causing hepatic dysfunction. Renal insufficiency (creatinine >1.5 mg/dL). Pregnancy & lactation.
Adverse Reactions
Nausea, vomiting. Adult/elderly: Hypotension. Childn: Agitation, increased cough. Elderly: Bradycardia.
Drug Interactions
Potentiated action of non-depolarizing muscle relaxants. Myocardial sensitization w/ exogenously administered adrenaline. Decreased MAC values w/ nitrous oxide. Increased metabolism by CYP2E1 inducers eg, INH, alcohol. Lesser conc w/ IV anaesth eg, propofol.
MIMS Class
Anaesthetics - Local & General
ATC Classification
N01AB08 - sevoflurane ; Belongs to the class of halogenated hydrocarbons. Used as general anesthetics.
Presentation/Packing
Form
Sojourn inhalation liqd 100% v/v
Packing/Price
250 mL x 1's
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