Serrapeptase: Indication, Dosage, Side Effect, Precaution

This information is not country-specific. Please refer to the Malaysia prescribing information.

Generic Medicine Info

Indications and Dosage

Oral
Inflammation, Oedema

Adult: In cases related to certain conditions such as trauma, infection, respiratory tract congestion, and chronic venous insufficiency: 5-10 mg (10,000-20,000 units) tid.

Administration

Should be taken on an empty stomach. Take 2 hr after meals.

Adverse Reactions

Gastrointestinal disorders: Gastric discomfort, nausea.
Metabolism and nutrition disorders: Anorexia.

Drug Interactions

May enhance the effect of anticoagulants.

Action

Description:
Mechanism of Action: Serrapeptase is a proteolytic enzyme of Serratia spp source. Experimental evidence to support the mechanism involved in its anti-inflammatory activity has not been published, however, it has been attributed to the hydrolysis of inflammatory mediators such as bradykinin, histamine, and serotonin.
Synonym: serratiopeptidase.

Storage

Store below 25°C.

MIMS Class

Anti-Inflammatory Enzymes

References

Anon. Serrapeptase (Natural Products Database). Lexicomp Online. Hudson, Ohio. Wolters Kluwer Clinical Drug Information, Inc. https://online.lexi.com. Accessed 17/11/2021.

Buckingham R (ed). Serrapeptase. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 17/11/2021.

Emanzen/Emanzen Forte (Emcure). MIMS Singapore. http://www.mims.com/singapore. Accessed 17/11/2021.

Serazen (New Life Pharma). MIMS Hong Kong. http://www.mims.com/hongkong. Accessed 17/11/2021.

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