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Acute pain
Adult: 0.2% soln: Lumbar epidural block: 20-40 mg (10-20 mL) as an initial bolus followed by 20-30 mg (10-15 mL) at intervals of not less than 30 min. Alternatively, 12-20 mg/hr (6-10 mL/hr) as a continuous epidural infusion. Doses up to 28 mg/hr (14 mL/hr) may be used if additional pain relief is required. Thoracic epidural block: 12-28 mg/hr (6-14 mL/hr) as a continuous infusion. Infiltration anaesth: 0.2% soln: 2-200 mg (1-100 mL); or 0.5% soln: 5-200 mg (1-40 mL).
Parenteral
Surgical anaesthesia
Adult: Lumbar epidural block: 0.5% soln: 75-150 mg (15-30 mL); 0.75% soln: 112.5-187.5 mg (15-25 mL); 1% soln: 150-200 mg (15-20 mL). Caesarean section: 0.5% soln: 100-150 mg (20-30 mL); 0.75% soln: 112.5-150 mg (15-20 mL). Thoracic epidural block to establish a block for post-op pain relief: 0.5% soln: 25-75 mg (5-15 mL); 0.75% soln: 37.5-112.5 mg (5-15 mL. Peripheral nerve block: 0.5% soln: 175-250 mg (35-50 mL); 0.75% soln: 225-300 mg (30-40 mL). Infiltration anaesth and field block: 0.5% soln: Up to 200 mg (40 mL); 0.75% soln: Up to 225 mg (30 mL).
