Promazine - oral

Patient Medicine Information
Why do I need this medicine?
Promazine is used together with other medicines to treat psychomotor agitation (unintentional and purposeless motions such as wringing of hands, or uncontrolled tongue movement, associated with mood disorders).

This medicine is also used to treat agitation and restlessness in elderly people.
How do I take this medicine?
Take Promazine exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Try to take it at the same time each day.

This medicine is available as tablet or as syrup.

If you are taking the tablet, swallow the tablet whole with a glass of water.

If you are taking an oral syrup, use the measuring spoon or cup provided to measure your dose.

Promazine must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it suddenly as this may worsen your condition.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Alert your doctor if you have phaeochromocytoma (rare tumour of the adrenal gland causing high blood pressure) as Promazine may not be suitable for you.

This medicine should not be given in patients who are in a coma or suffering from central nervous system depression (characterised as slow heart rate and breathing and loss of consciousness).

Do not take Promazine if you are pregnant or planning to have a baby soon. If you become pregnant while being treated with this medicine, alert your doctor immediately. Promazine may cause harm to your unborn child.

Do not take this medicine if you are breastfeeding.
What should I take note of while taking this medicine?
Inform your doctor if you have the following conditions:
  • blood disorders
  • severe lung disease
  • Parkinson’s disease (disorder that affects movement of a person, causing symptoms such as tremors, muscle stiffness, slowed movement and impaired balance or walking)
  • fits or seizures
  • diabetes
  • low thyroid hormone level
  • depression
  • myasthenia gravis (muscle weakness disorder)
  • enlarged prostate gland
  • glaucoma (increased pressure in the eye)
  • heart disease
  • kidney disease
  • liver disease
Be sure to check with your doctor or pharmacist before giving Promazine to an elderly. Elderly people may be more sensitive to the side effects.

This medicine may affect the ability of your body to adjust to temperature changes in the environment. Avoid exposure to very cold or very hot environments. Avoid strenuous exercise and activities like going to the sauna. Drink more water to prevent dehydration.
What side effects could I experience?
Promazine may cause drowsiness, dizziness or blurred vision. If affected, do not drive or take part in any activity in which you need to be alert or need to see clearly.

Other side effects include any of the following: headache, constipation, dry mouth, stuffy nose, rash, confusion, excitement, lack of interest, and eye problems.

This medicine may also make your skin more sensitive to sunlight. Apply sunscreen when going outdoors and avoid prolonged exposure to sunlight and UV lamps.

Some side effects may need immediate medical help. Although they are not common, alert your doctor quickly if you experience any of the following:
  • unusually fast heartbeat, unstable blood pressure
  • involuntary restless or repetitive limb movements, inability to stand still, shaking
  • very high body temperature, chills, muscle stiffness or change in consciousness
  • yellowing of the skin or eyes with fever
  • blood clots especially in the legs accompanied with swelling, pain and redness
  • lack of emotion
  • fits or seizures
  • shortness of breath, chest pain
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Inform your doctor and pharmacist if you are taking any of these medicines:
  • medicines for high blood pressure e.g. amlodipine
  • medicines for diabetes e.g. gliclazide
  • medicines for sleep disorder e.g. zopiclone
  • medicines for anxiety e.g. alprazolam
  • medicines for fits or seizures e.g. phenobarbital
  • medicines for irregular heartbeat e.g. amiodarone, sotalol, quinidine, disopyramide
  • certain antibiotics e.g. erythromycin, moxifloxacin
  • medicines for depression e.g. amitriptyline, maprotiline
  • medicines for cold or allergy e.g. terfenadine
  • medicines for malaria e.g. quinine
  • medicines for mood disorders e.g. haloperidol, lithium
  • cisapride (medicine used for certain stomach disorders)
  • tetrabenazine (medicine used for uncontrollable movements)
  • sibutramine (medicine used to help for weight loss)
  • metoclopramide (medicine to treat nausea and vomiting)
  • strong painkillers e.g. morphine
This list does not include all medicines that may interact with Promazine.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol. Alcohol intake may worsen the dizziness and drowsiness caused by Promazine.
How should I store this medicine?
Store in a cool, dry place away from the reach of children. Protect from light.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on promazine - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2023 MIMS. All rights reserved. Powered by
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