Sympathomimetics should be used with caution in patients with hypertension, hyperthyroidism, diabetes mellitus and cardiovascular disease. Antihistamines should be used with caution in patients with narrow angle glaucoma, stenosing peptic ulcer, pyloroduodenal obstruction, symptomatic prostatic hypertrophy and bladder neck obstruction. Patients should be warned about engaging in activities requiring mental alertness such as driving a car or operating machinery. Not recommended for children below 2 years. Use with caution and on doctor's/pharmacist's advice in children 2 to 6 years of age.
Effects on Ability to Drive and Use Machine: Patients should be warned about engaging in activities requiring mental alertness such as driving a car or operating machinery.
Use in Pregnancy and Lactation: Safety during pregnancy has not been established. It is not known whether Polarine Syrup is excreted in human milk and therefore caution should be exercised when administered to nursing mothers.
Use in Children: Syrup: Safety and effectiveness of Polarine Syrup have not been established in children below 2 years.
Use in the Elderly: Antihistamines may cause dizziness, sedation and hypotension in patients above 60 years. These patients are also more likely to have adverse reactions to sympathomimetics.