Pregnancy: Although studies in animals have not shown evidence of embryo toxicity or teratogenicity, the possible risk to humans caused by flumazenil during pregnancy has not been determined. Therefore, flumazenil should only be used during pregnancy if the possible benefit to the patient outweighs the potential risks for the foetus.
Lactation: It is not known whether this flumazenil is excreted in breast milk. For this reason, breast-feeding should be interrupted for 24 hours when flumazenil is used during lactation. Emergency use of flumazenil during lactation is not contraindicated.