Pharmaniaga Flumazenil 0.1 mg/mL Injection is indicated for the complete or partial reversal of the central sedative effects of benzodiazepines. It may therefore be used in anaesthesia and in intensive care in the following situations: In anaesthesia: Termination of hypnosedative effects in general anaesthesia induced and/or maintained with benzodiazepines in hospitalised patients.
Reversal of benzodiazepine sedation in short-term diagnostic and therapeutic procedures in ambulatory patients and hospitalised patients.
In intensive care situations: For diagnosis of intoxication with benzodiazepines or to rule out such intoxication.
As a diagnostic measure in unconsciousness of unknown origin to differentiate between involvement of benzodiazepines, other drugs or brain damage.
For specific reversal of the central effects of benzodiazepines in drug overdose (return to spontaneous respiration and consciousness in order to render intubation unnecessary or allow extubation).