Pregnancy: Careful consideration should be given before prescribing the product for pregnant patients. Opioid analgesics may depress neonatal respiration and cause withdrawal effects in neonates of dependent mothers.
As a precautionary measure, use of Paralgin/Paralgin Forte should be avoided during the third trimester of pregnancy and during labor.
Breastfeeding: Paralgin/Paralgin Forte is contraindicated in women during breastfeeding.
At normal therapeutic doses codeine and its active metabolite may be present in breast milk at very low doses and is unlikely to adversely affect the breast fed infant. However, if the patient is an ultra-rapid metabolizer of CYP2D6, higher levels of the active metabolite, morphine, may be present in breast milk and on very rare occasions may result in symptoms of opioid toxicity in the infant, which may be fatal.