Oxantel: Indication, Dosage, Side Effect, Precaution

This information is not country-specific. Please refer to the Malaysia prescribing information.

Generic Medicine Info

Indications and Dosage

Oral
Enterobiasis, Hookworm infections, Infection caused by Trichostrongylus orientalis

Adult: With pyrantel: 10-20 mg/kg as single dose
Child: With pyrantel; 10-20 mg/kg as single dose

Oral
Infection caused by Trichuris trichiura

Adult: 10-20 mg/kg as single dose; with pyrantel: 10-20 mg/kg as single dose
Child: 10-20 mg/kg as single dose; with pyrantel: 10-20 mg/kg as single dose

Adverse Reactions

Headache, abdominal pain, diarrhoea

Action

Description:
Mechanism of Action: Oxantel, an analogue of pyrantel, is a depolarizing neuromuscular blocking agent. It opens nonselective cation channels and induces activation of nicotinic acetylcholine receptors, which results in spastic paralysis of the worms.

MIMS Class

Anthelmintics

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