Not indicated in hypothyroidism, adrenocortical deficiency, hyperprolactinemia, pituitary or hypothalamic tumours. Ovarian hyperstimulation syndrome (OHSS); thromboembolic events; ovarian & other reproductive system neoplasms. Monitor carefully estradiol levels & ovarian response based on ultrasound prior to & during stimulation therapy. Interference w/ serum or urinary hCG leading to false +ve pregnancy result. Renal or hepatic impairment. Multiple & ectopic pregnancy. Pregnancy loss by miscarriage or abortion. Not to be used during pregnancy & lactation.