Ovidrel

Ovidrel

choriogonadotropin alfa

Manufacturer:

Merck

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Choriogonadotropin α
Indications/Uses
Adult women undergoing superovulation prior to assisted reproductive techniques (ART) eg, in vitro fertilization (IVF) & anovulatory or oligo-ovulatory women to trigger final follicular maturation & luteinisation after stimulation of follicular growth.
Dosage/Direction for Use
SC Women undergoing superovulation prior to ART eg, IVF 250 mcg 24-48 hr after the last administration of FSH or human menopausal gonadotropin prep, when optimal stimulation of follicular growth is achieved. Anovulatory or oligo-ovulatory women 250 mcg 24-48 hr after optimal stimulation of follicular growth is achieved; coitus is recommended on the day of & the day after inj.
Contraindications
Hypersensitivity. Hypothalamus & pituitary gland tumours; ovarian enlargement or cyst unrelated to polycystic ovarian disease; gynaecological haemorrhage of unknown aetiology; ovarian, uterine or mammary carcinoma; active thromboembolic disorders; primary ovarian failure, sexual organ malformations & uterine fibroid tumours incompatible w/ pregnancy; postmenopausal women.
Special Precautions
Not indicated in hypothyroidism, adrenocortical deficiency, hyperprolactinemia, pituitary or hypothalamic tumours. Ovarian hyperstimulation syndrome (OHSS); thromboembolic events; ovarian & other reproductive system neoplasms. Monitor carefully estradiol levels & ovarian response based on ultrasound prior to & during stimulation therapy. Interference w/ serum or urinary hCG leading to false +ve pregnancy result. Renal or hepatic impairment. Multiple & ectopic pregnancy. Pregnancy loss by miscarriage or abortion. Not to be used during pregnancy & lactation.
Adverse Reactions
Headache; abdominal pain & distention, nausea, vomiting; mild or moderate OHSS; inj site reactions.
MIMS Class
Trophic Hormones & Related Synthetic Drugs
ATC Classification
G03GA08 - choriogonadotropin alfa ; Belongs to the class of gonadotropins. Used as ovulation stimulants.
Presentation/Packing
Form
Ovidrel soln for inj 250 mcg/0.5 mL
Packing/Price
1's
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