Tobacco dependence by relieving nicotine craving & w/drawal symptoms facilitating smoking cessation in smokers motivated to quit. Aid to reduce smoking [Nicotine Assisted Reduction to Stop (NARS)].
Heavy smoker (≥20 cigarettes daily or first cigarette smoke w/in ≤30 min of waking up) 4 mg. Max daily dose: 24 gums in 24 hr. Light smoker (<20 cigarettes daily) 2 mg. Max daily dose: 30 gums in 24 hr. Dosing regime: 8-12 gum daily for at least 3 mth before gradual reduction.
May be taken with or without food: Chew gum slowly until the taste becomes strong or mild burning sensation is experienced, then rest it between the
gums & the cheek. When the taste fades, start chewing it again,
then rest it in a different place from the previous time. Repeat the
chewing routine until the taste does not return (about 30 min).
Recent MI, unstable or worsening angina including Prinzmetal's angina, severe cardiac arrhythmia, recent CVA &/or uncontrolled HTN; uncontrolled hyperthyroidism or phaeochromocytoma; oesophagitis, gastric or peptic ulcers. Monitor blood sugars in patients w/ DM. Moderate to severe hepatic &/or severe renal impairment. Pregnancy. Avoid use during lactation. Childn & adolescents <18 yr.
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