Posology: One tablet per 24 hours, preferably in the morning, to be swallowed whole with water and not chewed. At higher doses the antihypertensive action of indapamide is not enhanced but the saluretic effect is increased.
Special populations: Renal impairment (see Contraindications and Precautions): In severe renal failure (creatinine clearance below 30 ml/min), treatment is contraindicated.
Thiazide and related diuretics are fully effective only when renal function is normal or only minimally impaired.
Hepatic impairment (see Contraindications and Precautions): In severe hepatic impairment, treatment is contraindicated.
Elderly (see Precautions): In the elderly, the plasma creatinine must be adjusted in relation to age, weight and gender. Elderly patients can be treated with Natrilix SR 1.5 mg when renal function is normal or only minimally impaired.
Paediatric population: The safety and efficacy of Natrilix SR 1.5 mg in children and adolescents have not been established. No data are available.
Method of administration: Oral use.