Opioid dependence
Adult: As hydrochloride: Initially, 25 mg; increase to 50 mg daily if no withdrawal signs occur. Maintenance: 350 mg wkly given as 50 mg daily or divided in 3 doses (given on 3 days of the wk) for improved compliance.
Oral
Adjunct in alcohol dependence
Adult: As hydrochloride: 50 mg daily.