Myodeen

Myodeen

adenosine

Manufacturer:

Gland Pharma

Distributor:

Unimed
Concise Prescribing Info
Contents
Adenosine
Indications/Uses
Rapid conversion to a normal sinus rhythm of paroxysmal supraventricular tachycardia including those associated w/ accessory bypass tracts (Wolff-Parkinson-White syndrome). Aid to diagnosis of broad or narrow complex supraventricular tachycardia. Sensitization of intracavitary electrophysiological investigations.
Dosage/Direction for Use
Adult & elderly 1st dose: 3 mg rapid IV bolus over 2 sec. 2nd dose: 6 mg rapid IV bolus if supraventricular tachycardia is not attained w/in 1-2 min. 3rd dose: 12 mg rapid IV bolus if supraventricular tachycardia is not attained w/in 1-2 min.
Contraindications
Hypersensitivity. Sick sinus syndrome, 2nd or 3rd degree AV block, chronic obstructive lung disease w/ evidence of bronchospasm (eg, asthma bronchiole), long QT syndrome, severe hypotension, decompensated heart failure.
Special Precautions
Discontinue use if angina, severe bradycardia & hypotension, resp failure, asystole/cardiac arrest occur. Patients w/ left main coronary stenosis, uncorrected hypovolemia, stenotic valvular heart disease, left to right shunt, pericarditis or pericardial effusion, autonomic dysfunction or stenotic carotid artery disease w/ cerebrovascular insufficiency, recent MI, severe heart failure, minor conduction defects (1st degree AV & bundle branch block), atrial fibrillation or flutter, accessory bypass tract, prolonged QT intervals; history of seizures or susceptibility to seizures; bronchospasm. Patients on controlled Na diet. Recent & post heart transplant patients. Not to be administered w/ dipyridamole. Not recommended during pregnancy. Not to be used during lactation. Childn 0-18 yr.
Adverse Reactions
Bradycardia, sinus pause, skipped beats, atrial extrasystoles, AV block, ventricular excitability disorders eg, ventricular extrasystoles, non-sustained ventricular tachycardia; dyspnea; flushing; chest pressure/pain, feeling of thoracic constriction/oppression. Headache, dizziness, lightheadedness; nausea; burning sensation; apprehension.
Drug Interactions
Potentiated action by dipyridamole. Avoid use w/ theophylline & other xanthines; xanthine-containing foods & drinks; drugs impairing cardiac conduction.
MIMS Class
Cardiac Drugs
ATC Classification
C01EB10 - adenosine ; Belongs to the class of other cardiac preparations.
Presentation/Packing
Form
Myodeen soln for inj 3 mg/mL
Packing/Price
2 mL x 1's
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