Metrogyl Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Warnings Special Precautions Use In Pregnancy & Lactation Side Effects Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Metronidazole

Indications/Uses

Amoebic liver abscess, anaerobic bacterial infections. Tab: Symptomatic & asymptomatic trichomoniasis, intestinal amoebiasis, intra-abdominal, skin & skin structure, gynaecological, bone & joint, CNS & lower resp tract infections; bacterial septicemia, endocarditis. Oral susp: Amoebiasis, giardiasis.

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Dosage/Direction for Use

Tab Trichomoniasis 2 g as single dose or 800 mg in the morning & 1.2 g in the evening as 2-day course, or 600 mg-1 g daily in 2 or 3 divided doses as 7-day course. Amoebiasis 400-800 mg tds for 5-10 days. Anaerobic bacterial infections Adult 7.5 mg/kg every 6 hr for 7-10 days. Max: Not to exceed 4 g in 24 hr. Oral susp Childn 35-50 mg/kg daily in 3 divided doses for 10 days.

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Overdosage

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Contraindications

Hypersensitivity to metronidazole or other nitroimidazole derivatives. Tab: 1st trimester of pregnancy.

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Warnings

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Special Precautions

Severe hepatic diseases. Tab: Discontinue use if convulsive seizures & peripheral neuropathy occur. CNS diseases. Pregnancy & lactation. Childn.

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Use In Pregnancy & Lactation

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Adverse Reactions

Unpleasant metallic taste; leukopenia; flattening of T-wave; convulsive seizures, peripheral neuropathy, dizziness, vertigo, incoordination, ataxia, confusion, irritability, depression, weakness, insomnia; urticaria, erythematous rash, flushing, nasal congestion, dry mouth, fever; dysuria, cystitis, polyuria, incontinence, sense of pelvic pressure.

Drug Interactions

Tab: Potentiated effect of warfarin & other oral coumarin anticoagulants. Reduced plasma levels w/ drugs inducing microsomal enzymes eg, phenytoin or phenobarb. Impaired clearance of phenytoin. Prolonged t_½& decreased plasma clearance w/ cimetidine. Lithium toxicity. Psychotic reactions w/ disulfiram & alcohol.

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Storage

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Description

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Action

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MIMS Class

Antiamoebics

ATC Classification

P01AB01 - metronidazole ; Belongs to the class of nitroimidazole derivatives antiprotozoals. Used in the treatment amoebiasis and other protozoal diseases.

Regulatory Classification

Presentation/Packing

Form

Metrogyl FC tab 200 mg

Packing/Price

10's

Form

Metrogyl FC tab 400 mg

Packing/Price

10's

Form

Metrogyl oral susp 200 mg/5 mL

Packing/Price

100 mL x 1's;500 mL x 1's

Metrogyl

metronidazole

Manufacturer:

Unique Pharma Lab

Distributor:

Unimed