Monotherapy when diet & exercise alone do not provide adequate glycemic control in adult patients whom metformin is considered inappropriate due to intolerance. Add-on combination therapy w/ glucose-lowering medicinal products including insulin prep in adult patients w/ type 2 DM to improve glycemic control when diet & exercise + monotherapy does not provide adequate glycemic control.
View Lusefi overdosage for action to be taken in the event of an overdose.
Administration
May be taken with or without food: Take before or after breakfast.
Contraindications
Hypersensitivity. Patients w/ severe ketosis, diabetic coma or pre-coma; severe infection, those who underwent or are scheduled for surgeries, w/ serious trauma.
Discontinue use if ketoacidosis occur. Increased risk of hypoglycemia. Pituitary dysfunction or adrenal insufficiency; UTI, genital infection; diabetes-like symptoms eg, impaired glucose tolerance & +ve urinary glucose; presence or absence of infections; hypovolemia; dysuria, anuria, oliguria or urinary retention. Poor nutritional status, starvation, irregular diet, insufficient dietary intake or debility; strenuous muscular exercise; excessive wt loss. Ensure adequate hydration during treatment. Periodically check plasma glucose, renal function & other parameters during treatment. Excessive alcohol consumption. Concomitant use w/ sulfonylureas, insulin prep, diuretics or GLP-1 receptor agonists. May affect ability to drive & use machines. Not recommended in moderate to severe renal impairment. Severe hepatic dysfunction. Not to be used in women of childbearing potential or during pregnancy. Avoid use during lactation. Childn <20 yr. Elderly.
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