Hypertensive type 2 diabetic patient Initially 150 mg once daily, may be titrated up to 300 mg once daily. Patient undergoing haemodialysis Initially 75 mg.
Not recommended in primary aldosteronism. Bilateral renal artery stenosis or artery stenosis to single functioning kidney; hypertensive patients w/ type 2 diabetes & renal disease; aortic or mitral stenosis or obstructive hypertrophic cardiomyopathy; hyperkalaemia. Correct vol &/or Na depletion prior to administration. Periodic monitoring of serum K & creatinine levels. Not recommended in combination w/ lithium. Not recommended during 1st trimester of pregnancy & lactation.
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